Principal Research Scientist I-Genetic Characterization (Onsite, Worcester, MA)

Company: Hispanic Alliance for Career Enhancement
Location: Worcester
Posted on: June 1, 2025

Job Description:

Company DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on , , , , , and .Job DescriptionOperation PDST Biological Development and Launch at AbbVie is seeking a highly motivated Principal Scientist with a strong understanding of early and late-stage biological pipeline cell line development and genetic characterization to lead the Molecular Biology team at the AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers a unique setting where biologics drug discovery, development, and manufacturing coexist in one location. The leader will be responsible for asset transition from discovery into development, vector construct development, cell line development, cell bank genetic characterization and qualification, as well as modernizing traditional molecular biology methods through innovation and developing next-generation genetic characterization platform processes. Experience with cutting-edge technologies such as NGS, Omics, AI/ML, high-throughput automation, and digitalization for process optimization are preferred.Responsibilities:

• Develops and achieves discipline strategy in alignment with functional goals and key scientific objectives. Ensures the successful transition of AbbVie biological assets from discovery into development.
• Executes and guides the development and genetic characterization of cell lines and cell banks, supporting all pipeline development stages.
• Identifies and implements advanced technologies strategically to support accelerated biological pipeline programs.
• Provides strategic, operational, and scientific guidance to the molecular biology team.
• Conducts general laboratory research proficiently and independently, adapting and troubleshooting experimental designs and equipment to meet research requirements.
• Applies creative thinking to solve complex problems and promotes new technologies, effectively communicating mission and ideas to diverse audiences.
• Manages multiple projects across therapeutic disciplines within a dynamic and fast-paced team setting.
• Presents scientific concepts and results to scientific and non-scientific leaders, maximizing impact and value of expertise.
• Advances scientific expertise within the function, proactively sharing knowledge and mentoring colleagues to achieve business goals.Qualifications

• BS with 14+ years of experience, MS with 12+ years, or PhD with 6+ years in Biology, Molecular and Cellular Biology, or related fields.
• Strong interpersonal skills to collaborate with diverse groups and maintain internal and external relationships.
• Broad experience in cell line development across various cell types, with a proven record of contributing to drug candidate development.
• Expertise in molecular biology techniques for plasmid construction and genetic characterization.
• Proven ability to innovate with new or improved methods or workflows.
• Strong attention to quality, detail, and effective communication within collaborative environments.Additional InformationThe compensation range described is based on the job grade and may vary depending on location and other factors. We offer comprehensive benefits including paid time off, medical/dental/vision insurance, and 401(k). This role is eligible for short-term and long-term incentive programs. All compensation is subject to change and depends on company policies and individual negotiations.AbbVie is an equal opportunity employer committed to diversity and inclusion. For more information, visit . Applicants seeking accommodations can learn more at .
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